← BICYCLE THERAPEUTICS PLC

Annual Trend FY 2017 FY 2018 FY 2019 FY 2020 FY 2021 FY 2022 FY 2023 FY 2024 FY 2025
Cash flows from operating activities:
Adjustments to reconcile net income to net cash provided by operating activities:
Net Income From Continuing Operations — — — — — ($112.7m) ($180.7m) ($169.0m) ($219.0m)
Net Income (Loss) Attributable to Parent — ($21.8m) ($30.6m) ($51.0m) ($66.8m) ($112.7m) ($180.7m) ($169.0m) ($219.0m)
Net Income (Loss) Available to Common Stockholders, Basic — ($21.8m) ($30.6m) ($51.0m) ($66.8m) ($112.7m) ($180.7m) ($169.0m) ($219.0m)
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest — ($21.8m) ($30.6m) ($51.0m) ($66.8m) ($112.7m) ($180.7m) ($169.0m) ($219.0m)
Depreciation, Depletion and Amortization $332k $712k $960k $1.3m $1.4m $3.7m $6.5m $7.2m $6.4m
Depreciation $332k $700k $1.0m $1.3m $1.4m $3.7m $6.5m $7.2m $6.4m
Depreciation Amortization Depletion — — — — — $3.7m $6.5m $7.2m $6.4m
Deferred Income Tax Expense (Benefit) — ($378k) ($364k) ($673k) ($1.7m) ($5.0m) $3.3m ($5.2m) ($850k)
Deferred income tax (benefit) provision — — — ($673k) ($1.7m) ($5.0m) $3.3m ($5.2m) ($850k)
Deferred Income Tax — — — — — ($5.0m) $3.3m ($5.2m) ($850k)
Deferred Tax — — — — — ($5.0m) $3.3m ($5.2m) ($850k)
Share-based Payment Arrangement, Noncash Expense — $1.0m $3.1m $6.5m $12.1m $26.8m $32.5m $38.1m $39.5m
Share-based Payment Arrangement, Expense — $1.0m $3.1m $6.5m $12.1m $26.8m $32.5m $38.1m $39.5m
Share-based compensation expense $515k $1.0m $3.1m $6.5m $12.1m $26.8m $32.5m $38.1m $39.5m
Gain (Loss) on Extinguishment of Debt — — — — — — — ($954k) —
Income Tax Expense (Benefit) — ($396k) ($254k) ($724k) ($1.7m) ($1.5m) $1.5m ($4.8m) $152k
Interest Expense Nonoperating — — — — — — — $1.7m $206k
Other Nonoperating Income (Expense) — ($665k) ($5.4m) — — — — — —
Operating lease rightofuse assets — — $712k $771k $404k $2.7m $4.2m $4.4m $4.6m
Operating lease liabilities — — ($709k) ($621k) ($582k) ($2.1m) ($4.1m) ($4.9m) ($5.5m)
Changes in operating assets and liabilities:
Additional Financial Items
Increase (Decrease) in Accounts Receivable — $400k ($4.9m) $2.1m ($4.5m) $1.6m ($2.5m) — —
Increase (Decrease) in Accounts Payable — ($169k) $220k ($663k) $1.2m $2.6m $8.0m $3.1m ($6.9m)
Proceeds from Stock Options Exercised — $1k $143k $271k $7.2m $989k $682k $7.5m $37k
Foreign Currency Transaction Gain (Loss), before Tax — — — — — ($600k) ($600k) ($700k) $700k
Foreign Currency Transaction Gain (Loss), Realized — $300k $900k $600k $400k — — — —
General and Administrative Expense — $8.1m $14.6m $29.2m $32.4m $49.5m $60.4m $72.2m $79.4m
Nonoperating Income (Expense) — ($496k) ($4.6m) $226k ($2.9m) $2.4m $10.7m $36.1m $28.3m
Operating Expenses — $28.9m $40.1m $62.4m $77.3m $131.1m $216.9m $245.1m $319.7m
Net loss ($16.3m) ($21.8m) ($30.6m) ($51.0m) ($66.8m) ($112.7m) ($180.7m) ($169.0m) ($219.0m)
Non-cash interest — — — $78k $468k $442k $383k $211k —
Other non-cash charges — — — — — — $661k $1.0m —
Accounts receivable — ($400k) $4.9m ($2.1m) $4.5m ($1.6m) $2.5m — —
Research and development incentives receivable ($1.4m) ($3.6m) ($383k) ($1.8m) ($1.9m) ($9.7m) ($3.7m) ($11.9m) $2.9m
Prepaid expenses and other assets ($330k) ($1.3m) ($2.7m) ($49k) ($3.0m) ($2.0m) ($2.1m) ($2.0m) ($5.8m)
Accounts payable $67k ($169k) $220k ($663k) $1.2m $2.6m $8.0m $3.1m ($6.9m)
Accrued expenses and other current liabilities $1.3m $2.6m ($852k) $4.8m $1.2m $12.4m $2.4m $9.7m $4.1m
Deferred revenue $14.1m ($3.9m) ($9.3m) $24.6m $37.1m ($2.1m) $69.0m ($32.0m) ($69.2m)
Other long-term liabilities $383k $543k $1.1m $517k $710k $668k $509k $189k —
Proceeds from the issuance of ADSs and non-voting ordinary shares, net of issuance costs — — — $48.1m $7.6m $5.7m $249.3m $544.1m —
Proceeds from the exercise of share options and settlement of restricted share units $1k $1k $143k $271k $7.2m $989k $682k $7.5m $37k
Principal payments on finance lease obligations — — — — — — — ($42k) ($168k)
Restricted cash included in other assets — — — — — $0 $547k $547k $58k
Changes in purchases of property and equipment in accounts payable and accrued expenses — — — — $324k $1.6m ($1.7m) ($4k) —
Property and equipment obtained under finance leases — — — — — — — $1.1m —
Beginning Cash Position — — — — — $438.7m $339.2m $527.0m $880.1m
Cash Flow From Continuing Financing Activities — — — — — $6.7m $250.0m $519.8m ($131k)
Cash Flow From Continuing Investing Activities — — — — — ($19.0m) ($2.9m) ($1.2m) ($2.4m)
Change In Account Payable — — — — — $2.6m $8.0m $3.1m ($6.9m)
Change In Accrued Expense — — — — — $12.4m $2.4m $9.7m $4.1m
Change In Other Current Assets — — — — — $2.7m $4.2m $4.4m $4.6m
Change In Other Current Liabilities — — — — — ($1.4m) ($3.6m) ($4.7m) ($5.5m)
Change In Other Working Capital — — — — — ($2.1m) $69.0m ($32.0m) ($69.2m)
Change In Payable — — — — — $2.6m $8.0m $3.1m ($6.9m)
Change In Payables And Accrued Expense — — — — — $14.9m $10.4m $12.8m ($2.8m)
Change In Prepaid Assets — — — — — ($2.0m) ($2.1m) ($2.0m) ($5.8m)
Change In Receivables — — — — — ($11.3m) ($1.2m) ($11.9m) $2.9m
Change In Working Capital — — — — — $672k $76.7m ($33.4m) ($75.8m)
Changes In Account Receivables — — — — — ($1.6m) $2.5m $0 $0
Changes In Cash — — — — — ($98.4m) $186.5m $353.8m ($252.2m)
End Cash Position — — — — — $339.2m $527.0m $880.1m $628.7m
Financing Cash Flow — — — — — $6.7m $250.0m $519.8m ($131k)
Free Cash Flow — — — — — ($105.1m) ($63.6m) ($166.0m) ($252.0m)
Investing Cash Flow — — — — — ($19.0m) ($2.9m) ($1.2m) ($2.4m)
Issuance Of Capital Stock — — — — — $5.7m $249.3m $544.1m $0
Net PPE Purchase And Sale — — — — — ($19.0m) ($2.9m) ($1.2m) ($2.4m)
Other Non Cash Items — — — — $468k $442k $1.0m ($3.2m) —
Proceeds From Stock Option Exercised — — — — — $989k $682k $7.5m $37k
Purchase Of PPE — — — — — ($19.0m) ($2.9m) ($1.2m) ($2.4m)
Stock Based Compensation — — — — — $26.8m $32.5m $38.1m $39.5m
Net Cash Provided by (Used in) Operating Activities ($1.4m) ($26.1m) ($28.6m) ($17.8m) ($14.8m) ($86.1m) ($60.6m) ($164.7m) ($249.7m)
Cash flows from investing activities:
Payments to Acquire Property, Plant, and Equipment ($1.1m) $1.2m $1.6m $1.2m $2.0m $19.0m $2.9m $1.2m $2.4m
Net Cash Provided by (Used in) Investing Activities ($1.1m) ($1.2m) ($1.6m) ($1.2m) ($2.0m) ($19.0m) ($2.9m) ($1.2m) ($2.4m)
Cash flows from financing activities:
Issuance Of Debt — — — — $15.0m $0 $0 — —
Long Term Debt Issuance — — — — $15.0m $0 $0 — —
Net Issuance Payments Of Debt — — — — — $0 $0 ($31.9m) ($168k)
Net Long Term Debt Issuance — — — — — $0 $0 ($31.9m) ($168k)
Repayments of Long-term Debt — — — — — — — $31.9m —
Long Term Debt Payments — — — — — $0 $0 ($31.9m) ($168k)
Repayment Of Debt — — — — — $0 $0 ($31.9m) ($168k)
Proceeds from Issuance of Common Stock — — — — $7.6m $5.7m $249.3m $544.1m —
Common Stock Issuance — — — — — $5.7m $249.3m $544.1m $0
Net Common Stock Issuance — — — — — $5.7m $249.3m $544.1m $0
Net cash (used in) provided by financing activities $57.9m $25.4m $58.4m $62.8m $320.7m $6.7m $250.0m $519.8m ($131k)
Net Cash Provided by (Used in) Financing Activities — $25.4m $58.4m $62.8m $320.7m $6.7m $250.0m $519.8m ($131k)
Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents — ($2.4m) $465k $19k ($1.2m) — — — —
Effect of exchange rate changes on cash, cash equivalents and restricted cash — — — $19k ($1.2m) ($1.1m) $1.3m ($694k) $804k
Effect Of Exchange Rate Changes — — — — — ($1.1m) $1.3m ($694k) $804k
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect — ($4.3m) $28.7m $43.9m $302.7m ($99.5m) $187.8m $353.1m ($251.4m)
Net increase (decrease) in cash, cash equivalents and restricted cash $58.3m ($4.3m) $28.7m $43.9m $302.7m ($99.5m) $187.8m $353.1m ($251.4m)
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents — $63.4m $92.1m $136.0m $438.7m $339.2m $527.0m $880.1m $628.7m
Cash, cash equivalents and restricted cash at beginning of period $67.7m $63.4m $92.1m $136.0m $438.7m $339.2m $527.0m $880.1m $628.7m
Cash and cash equivalents — — — — $438.7m $339.2m $526.4m $879.5m $628.1m
Supplemental disclosure of cash flow information:
Change In Cash Supplemental As Reported — — — — — ($99.5m) $187.8m $353.1m ($251.4m)
Interest Paid, Excluding Capitalized Interest, Operating Activities — — — $378k $2.5m $2.8m $2.8m $1.4m $78k
Income Taxes Paid, Net — $73k $117k $124k $73k $2.2m $562k $792k ($717k)

Data sourced from SEC EDGAR 10-K filings via EdgarTools. Amounts are shown in USD as reported in each fiscal year filing.