|
Net income (loss)
|
|
($23.8m)
|
($33.5m)
|
($28.7m)
|
($44.2m)
|
($36.2m)
|
($25.0m)
|
$35.5m
|
$190.3m
|
|
Depreciation and amortization expense
|
|
$769k
|
$1.2m
|
$1.6m
|
$1.8m
|
$3.5m
|
$8.2m
|
$19.8m
|
$27.2m
|
|
Deferred taxes
|
|
—
|
—
|
—
|
—
|
—
|
($1.7m)
|
—
|
($83.5m)
|
|
Non-cash interest expense and end of term accretion expense
|
|
$177k
|
$475k
|
$511k
|
$540k
|
$465k
|
$2.1m
|
$3.1m
|
$3.1m
|
|
Operating lease liabilities
|
|
—
|
—
|
—
|
$236k
|
$255k
|
($1.6m)
|
($2.3m)
|
($2.9m)
|
|
Operating lease liabilities arising from obtaining right-of-use assets
|
|
—
|
—
|
—
|
—
|
—
|
$2.2m
|
$1.5m
|
$795k
|
|
Stock-based compensation expense
|
|
$144k
|
$854k
|
$2.4m
|
$6.9m
|
$10.3m
|
$19.8m
|
$33.2m
|
$36.9m
|
|
Acquired in-process research and development expenses
|
|
—
|
—
|
—
|
—
|
—
|
$27.2m
|
—
|
—
|
|
Non-cash lease expense
|
|
—
|
—
|
—
|
$829k
|
$717k
|
$1.0m
|
$1.6m
|
$2.1m
|
|
Unrealized foreign currency transaction (gains) losses
|
|
$150k
|
$200k
|
($1.1m)
|
$928k
|
$1.1m
|
($342k)
|
$665k
|
($1.6m)
|
|
Loss on disposal of fixed assets
|
|
—
|
—
|
—
|
—
|
—
|
—
|
$17k
|
$80k
|
|
Accounts receivable
|
|
($2.5m)
|
($3.2m)
|
($218k)
|
$840k
|
($21.7m)
|
($33.8m)
|
($34.3m)
|
$13.9m
|
|
Inventory
|
|
($2.7m)
|
($4.1m)
|
($1.7m)
|
($4.9m)
|
($8.0m)
|
($28.1m)
|
($8.4m)
|
($7.7m)
|
|
Prepaid expenses and other current assets
|
|
($1.4m)
|
$250k
|
($769k)
|
($3.2m)
|
$2.5m
|
($2.1m)
|
($6.3m)
|
($3.8m)
|
|
Other non-current assets
|
|
—
|
—
|
—
|
—
|
—
|
($54k)
|
($149k)
|
($23k)
|
|
Accounts payable
|
|
$164k
|
$3.4m
|
($5.8m)
|
$5.1m
|
($3.3m)
|
$7.0m
|
($1.4m)
|
($19k)
|
|
Accrued expenses and other current liabilities
|
|
$2.3m
|
$2.5m
|
$1.9m
|
$4.9m
|
$3.4m
|
$14.2m
|
$7.9m
|
$17.7m
|
|
Deferred revenue
|
|
$67k
|
($136k)
|
$60k
|
$7k
|
—
|
$83k
|
($203k)
|
$1.1m
|
|
Purchase of in-process research and development assets
|
|
—
|
—
|
—
|
—
|
—
|
($27.2m)
|
—
|
—
|
|
Proceeds from issuance of convertible senior notes, net of issuance costs paid of $14,620
|
|
—
|
—
|
—
|
—
|
—
|
$445.4m
|
—
|
—
|
|
Purchases of capped calls related to convertible senior notes
|
|
—
|
—
|
—
|
—
|
—
|
($52.1m)
|
—
|
—
|
|
Tax withholding payments related to net settlement of restricted stock units
|
|
—
|
—
|
—
|
—
|
—
|
—
|
—
|
($138k)
|
|
Purchases of property, plant and equipment included in accounts payable and accrued expenses
|
|
—
|
$169k
|
—
|
$1.2m
|
$62k
|
$2.5m
|
$2.1m
|
$1.8m
|
|
Conversion of convertible senior notes into common stock
|
|
—
|
—
|
—
|
—
|
—
|
—
|
$4k
|
—
|
|
Cash
|
|
—
|
—
|
—
|
—
|
—
|
$394.8m
|
$336.6m
|
$488.4m
|
|
Net cash provided by (used in) operating activities
|
|
($26.0m)
|
($32.3m)
|
($30.3m)
|
($28.9m)
|
($45.8m)
|
($13.0m)
|
$48.8m
|
$192.8m
|
|
Purchases of property, plant and equipment
|
|
($418k)
|
($165k)
|
($455k)
|
($3.5m)
|
($11.9m)
|
($151.8m)
|
($129.7m)
|
($59.3m)
|
|
Transfers of inventory to property, plant and equipment
|
|
$1.4m
|
$2.1m
|
$1.2m
|
$1.8m
|
$2.1m
|
$4.6m
|
$5.8m
|
$5.7m
|
|
Purchase of business, net of cash acquired
|
|
—
|
—
|
—
|
—
|
—
|
($14.9m)
|
$441k
|
—
|
|
Net cash used in investing activities
|
|
$12.3m
|
($60.5m)
|
($41.6m)
|
$29.3m
|
$54.5m
|
($194.0m)
|
($129.3m)
|
($59.3m)
|
|
Proceeds from issuance of common stock upon exercise of stock options
|
|
$46k
|
$202k
|
$227k
|
$974k
|
$4.7m
|
$6.2m
|
$20.8m
|
$13.7m
|
|
Proceeds from issuance of common stock in connection with employee stock purchase plan
|
|
—
|
—
|
$357k
|
$419k
|
$509k
|
$955k
|
$2.1m
|
$3.2m
|
|
Net cash provided by financing activities
|
|
$22.1m
|
$92.7m
|
$75.5m
|
$1.4m
|
$167.9m
|
$400.4m
|
$22.9m
|
$16.9m
|
|
Effect of exchange rate changes on cash and restricted cash
|
|
($82k)
|
($85k)
|
$803k
|
($797k)
|
($1.0m)
|
$193k
|
($536k)
|
$1.3m
|
|
Net increase (decrease) in cash and restricted cash
|
|
$8.3m
|
($149k)
|
$4.5m
|
$999k
|
$175.6m
|
$193.6m
|
($58.2m)
|
$151.7m
|
|
Cash and restricted cash, beginning of period
|
|
$20.7m
|
$20.6m
|
$25.1m
|
$26.1m
|
$201.7m
|
$395.3m
|
$337.1m
|
$488.9m
|
|
Cash and cash equivalents
|
|
—
|
$20.1m
|
$24.6m
|
$25.6m
|
$201.2m
|
$394.8m
|
—
|
—
|
|
Restricted Cash
|
|
—
|
$500k
|
$500k
|
$500k
|
$500k
|
$500k
|
$500k
|
$500k
|
|
Cash paid for interest
|
|
$2.4m
|
$3.9m
|
$3.5m
|
$3.3m
|
$3.3m
|
$8.1m
|
$11.3m
|
$10.7m
|